External Collection
- Access to: A comprehensive pathway map of epidermal growth factor receptor signaling
The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells. The comprehensive pathway map of EGFR signaling and other related pathways are represented. The map reveals that the overall architecture of the pathway is a bow-tie (or hourglass) structure with several feedback loops.
Oda K., Matsuoka Y., Kitano H. A comprehensive pathway map of epidermal growth factor receptor signaling. Mol Syst Biol 2005 1: 2005.0010. PMID